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This review synthesizes current evidence and highlights the underlying molecular mechanisms responsible for the observed effects, aiming to support the rational development of curcumin-based strategies in gynecology

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However, in addition to their ability to directly interact with biological molecules (lipids, proteins or nucleic acids), ROS damage also involves the alteration of signaling pathways, such as activation of the NF- pathway, which in turn activates the gene expression of several pro-inflammatory cytokines [16,19,26]

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Fe is known to induce oxidative stress, leading to damage in proteins, DNA, and lipids 38