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* Correspondence: Marco de Scordilli, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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A theoretical hypothesis proposes that pre-activated immune cells may preferentially home to tissues vulnerable to microcirculatory disturbances, such as erectile tissue (84, 100, 101)