For patients managing chronic inflammation as part of a broader longevity strategy, BPC-157 may fit alongside compounds like Low Dose Naltrexone (LDN), which modulates immune activity through a separate mechanism involving endorphin and toll-like receptor signaling, and metabolic interventions that address the upstream drivers of inflammaging
Wachter, A., Wolf, S., Steininger, H., Bogs, J., Rausch, T
Wuertzm S, Reiser S
However, in hepatocytes the majority of the acetyl-CoA is not oxidized by the TCA cycle but is metabolized into the ketone bodies, acetoacetate and -hydroxybutyrate
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They are not an EFSA opinion