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While the more obvious route would be directly suppressing TNF, that might not be a good idea because of its important roles in fighting infections and other invaders, which is already a concern for current treatments, they say

The effect of pentadecapeptide BPC-157 was shown to correspond to improvement after local application of bone marrow or autologous cortical graft

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Thats where BPC 157 for back pain comes in

Chronic Spine Pain: Whether from disc degeneration, facet joint disease, or muscular dysfunction, peptides can address the underlying tissue pathology contributing to persistent back and neck pain