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PubMed, Tanaka, Toshiko, et al

(2011) Insulin/IGF-1 receptor signaling enhances biosynthetic activity and fat mobilization in the initial phase of starvation in adult male C

Patients with stage 2 hypertension (moderate or severe) are at a relatively higher risk for cardiovascular events (such as strokes, heart attacks, and heart failure), kidney failure and vision problems, so prompt treatment is clinically relevant

Shibayama et al

These were prolonged QTc intervals [89], gastric lesions, and lower esophageal sphincter and pyloric sphincter dysfunction induced by dopamine receptor antagonists [68,92,165,172], as well as gastric lesions induced by combined application of dopamine receptor antagonist and reserpine [166]