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A confounding factor, as indicated in this study, is whether other forms of drug use may contribute to adverse cardiovascular effects, said Hoang Nguyen, MD, an interventional cardiologist at MemorialCare Heart & Vascular Institute at Orange Coast Medical Center in Fountain Valley, CA, who was not involved in the research

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Tobacco products with menthol can also be more addictive and harder to quit

So with a lot of parts that can malfunction and having to fill the liquid yourself, the larger vapes can have issues with leaking and come with a number of other time considerations

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