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Tanaka C, Coling DE, Manohar S, Chen GD, Hu BH, Salvi R, Henderson D

prolonged insufficient sleep is associated with numerous increased health concerns, including anxiety, depression, cardiovascular disease, stroke, and heart attack

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Previous studies have demonstrated that neutrophilic inflammation and MPO activity in the lung and sputum of COPD patients correlate well with disease progression (Park et al., 2013