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A spectrum of solutions: unveiling non-pharmacological approaches to manage autism spectrum disorder

Small molecules targeting lipid metabolism: The antitumor agent sorafenib, in the presence of ACSL4, activates ferroptosis by directly affecting lipid ROS generation pathways (121)

[DOI] [PubMed] [Google Scholar] 128.Esposito P., Chandler N., Kandere K., Basu S., Jacobson S., Connolly R., Tutor D., Theoharides T.C

Cell 182 , 13281340 (2020)

But a trial testing if it could slow Parkinson's progression over 5 years didn't find that it helped

The METTL3 inhibitor STM2457 promotes GPX4 degradation by reducing m6A modification, inducing ferroptosis and inhibiting metastasis in TNBC [89]