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Tract Symptoms 16 , e12508 (2024)

Antioxidants 10:364 Vallverd-Queralt A, Verbaere A, Meudec E, Cheynier V, Sommerer N (2015) Straightforward method to quantify GSH, GSSG, GRP, and hydroxycinnamic acids in wines by UPLC-MRM-MS

Ann Rheum Dis 82:4856

Practical applications

The mechanism involves modulation of dopamine and serotonin systems alongside promotion of nerve growth factor

Valsartan was without grossly observable adverse effects at single oral doses up to 2000 mg/kg in rats and up to 1000 mg/kg in marmosets, except for the salivation and diarrhea in the rat and vomiting in the marmoset at the highest dose (60 and 37 times, respectively, the MRHD on a mg/m2 basis) (Calculations assume an oral dose of 320 mg/day and a 60 kg patient)