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The appearance of a pustular/papular rash associated with high levels of Vitamin B12 is well described in the medical literature even though the exact mechanism appears to be unknown

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Tom Biernacki, DPM, FACFAS answers: Burning feet that worsen at night classic Grierson-Gopalan syndrome are most commonly caused by peripheral neuropathy from diabetes, vitamin B12 or B1 deficiency, or chronic alcohol use