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In antiestrogen-resistant LCC9 human breast cancer cells, the combination of JEKHT with 4-OHT can increase the sensitivity of the cells to TAM (De Oliveira Andrade et al., 2019)
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Proper dosing, consistent administration, and adequate duration all determine success
The conservative approach involves using DSIP for defined periods (10 to 20 days) followed by equal or longer breaks, similar to other peptide cycling strategies
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