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Subcutaneous injection provides optimal bioavailability for systemic effects, while topical application targets localized skin concerns

The half-life data doesnt clearly support a specific timing strategy

doi: 10.1016/j.neulet.2017.06.051 13 BarnettM

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But if your deficiency is caused by an absorption problem, lifestyle tweaks will not replace the injection schedule, they only support it

After a single dose of FOXO4-DRI, more than half of the senescent cells disappeared