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Lower GSH levels have been reported in the frontal grey matter of the brain of post-acute sequelae of COVID-19 (PASC) participants, suggesting ongoing oxidative stress in the brains of individuals with PASC 65

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There are three isoforms of CPTI, each present in characteristic tissues, CPTIA in liver and kidney, CPTIB in heart and skeletal muscle and CPTIC in the brain, and while CPTIA and CPTIB are the main enzymes for the transfer of long-chain fatty acids into mitochondria for oxidation, the lesser-known CPTIC may be a sensor of lipid metabolism in neurons

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