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The biotransformation that leads to the delayed formation of thiomethyl metabolites via the thiomethyl shunt pathway has been shown to occur in rodents via the enterohepatic circulation and biliary excretion of the glutathione-derived conjugates into the intestine ( 9 )

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Human Gene Therapy, 30 (7), 814828

Although MT-II is not approved for human use, it is under active research for potential uses in skin tanning and sexual health [6, 7]

10.3390/ijms25105375 [DOI] [PMC free article] [PubMed] [Google Scholar] Rahman M., Akter K., Ahmed K

Maintenance doses may be required every few months to sustain results