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Abdominal pain and cramping Diarrhea, often with pus and blood Rectal bleeding Urgency to defecate Rectal pain Fatigue (due to mitochondrial involvement) Weight loss Fever Failure to grow (in children) Ulcerative colitis can lead to some severe health complications

doi: 10.1016/j.nutres.2007.12.001

Oxidative/electrophilic stress sensor Keap1 regulates the rapid turnover of transcripition factor Nrf2

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It is fairly quickly cleared from the circulation, though, with a half-life of around 30 minutes

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