Mayer, P., Tolls, J., Hermens, J
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Yes, it should always be administered by trained professionals
While research shows some benefits (for example improved sleep efficiency, reduced sleep latency) in controlled settings, there are still questions around long-term safety, especially in healthy subjects or non-clinical contexts
Studies have examined GHK-Cu application after CO2 laser resurfacing and found accelerated healing and improved cosmetic outcomes, though these studies predate current clinical trial standards
Taken together, the researchers concluded that thyroid function may affect mast cells, and that mast cell degranulation could affect thyroid function.[ref] In patients with autoimmune thyroid disease, mast cells infiltrate the thyroid gland and then degranulate.[ref] Animal studies show that hypothyroidism (low thyroid hormone levels) increases the number of mast cells by up to 4.5-fold