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Ricci G, Del Boccio G, Pennelli A, Lo Bello M, Petruzzelli R, Caccuri AM et al

Detailed analysis of atpenin A5 and phenformin cytotoxicity and inhibition of metabolic activity in various cell lines As predicted from our modeling approach as tier 1 targets, atpenin A5 at 20 M and phenformin at 100 M do not show toxicity in endpoint measurements based on total cell counting when Calu-3, CaCo-2, A549, and Huh7.5 cells were exposed to the compounds for 72 h (Fig

To evaluate this pathway in the emphysema model, the expression of Nrf2 and Keap1 protein was measured by western blotting in the cytoplasm and nucleus, respectively

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V : amount of sample homogenate added (mL)

Although severe complications are rare, working with a qualified and experienced provider is crucial