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220 Paez-EspinoDEloe-FadroshEAPavlopoulosGAThomasADHuntemannMMikhailovaNet al

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CHE has been used as an inhibitor of Bcl-2 family proteins (Herbert et al., 1990) and could significantly inhibit cell proliferation in tumor cells, inducing cell apoptosis by adjusting the expression of Bcl-2 family proteins and activating the pathway of mitochondrial apoptosis (Zhang et al., 2011)

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