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Folate deficiency caused by a lack of dietary folate is more common in people who have a generally unbalanced and unhealthy diet, people who regularly misuse alcohol, and people following a restrictive diet that does not involve eating good sources of folate

Temperature fluctuations, light exposure, or contamination can shorten effective life significantly

O'Hollaren detailed the effective use of IV-infused NAD+ for the prevention, relief, or treatment of acute and chronic symptoms of addiction to a range of substances, including alcohol, heroin, opium extract, morphine, dihydromorphine, meperidine, codeine, cocaine, amphetamines, barbiturates, and tranquilizers (18)

Talk to your healthcare provider if you have unusual or severe adverse effects

The short answer is that preclinical evidence is compelling, though human clinical trial data remains limited

Always consult with a healthcare professional before starting any new supplement regimen