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[15] Modeling data: A model developed by researchers at UC Irvine showed that smoking prevalence for 15-17 year olds would drop from 22% to 9% in only seven years if the age of purchase were increased to 21 across the U.S

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Scrublet [42] was then applied to each sequencing library to remove potential doublets with the expected doublet rate of 7.6%, and cells with doubletScore larger than 90% quantile were filtered out

Pennsylvania, New Jersey, and Delaware all benefited from a major settlement of federal lawsuits filed by states against tobacco companies over the health effects of cigarette smoking