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doi: 10.1016/j.carres.2012.03.013 216 MedzhitovR

These include elevated levels of c-reactive protein (CRP), IL-6, and increased monocyte counts, suggesting that circadian disruption through NSW may promote a pro-inflammatory and pro-tumorigenic immune environment 138

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In humans, pantothenic acid deficiency has been induced experimentally by co-administering a pantothenic acid antagonist and a pantothenic acid-deficient diet