Gout and pseudogout-related crystals promote GLUT1-mediated glycolysis that governs NLRP3 and interleukin-1 activation on macrophages
300 , R428436 (2011)
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Patients in this study ranged from Type II to Type V
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Under normoxia and high glucose availability, most acetyl-CoA is produced from glucose-derived pyruvate via pyruvate dehydrogenase and exported as citrate for lipid synthesis