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However, the exact amount can be adjusted based on your specific research protocols needs

The primary concern with hepatic impairment is a potential change in exposure to a drug that is extensively cleared by hepatic metabolism or biliary excretion via the liver, that could impact on the pharmacodynamic action or lead to adverse effects [19]

doi: 10.1016/j.jcm.2012.11.001

10.1080/15592294.2024.2400423 5 AtanasovA

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This adjustment period can vary among individuals, with some experiencing quicker relief than others, depending on their overall health and dietary habits