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Nicotine acts as a stimulant in low doses but can be a nervous system depressant in high doses -- in extremely high doses it can depress the respiratory system enough to be lethal
With the arrival of the Europeans in the 16th century, the consumption, cultivation, and trading of tobacco quickly spread
Drought stress triggers the activation of abscisic acid (ABA)-dependent and independent signaling pathways in tobacco plants, which regulate the expression of related genes ( Reactive oxygen species (ROS) act as signaling molecules and damaging agents in plant stress responses ( Studies have shown that Late Embryogenesis Abundant (LEA) protein genes in tobacco are significantly upregulated under drought stress
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Both caffeine and nicotine stimulate the central nervous system, increasing alertness and influencing mood and cognition, though they do so in slightly different ways
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