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Woo KS, Chook P, Lolin YI, Sanderson JE, Metreweli C, and Celermajer DS (1999)

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21 Moreover, extracellular lactate-induced H3K18la in T helper 17 (Th17) cells, a subset of CD4 + T helper cells secreting IL-17, contributes to transforming pro-inflammatory T cells into Treg cells

Side effects are generally mild, including transient injection-site reactions or mild nausea