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c-Myc not only promotes the expression of LDHA to convert pyruvate to lactate, thereby promoting the extramitochondrial metabolism of pyruvate, but also increased the expression of mitochondrial transcription factor A and increases mitochondrial mass [142, 143]

When tissues sustain damage, GHK-Cu is released from extracellular matrix proteins including SPARC and collagen, functioning as a matrikine, a signal molecule that activates repair mechanisms

Ellagic acid in Emblica officinalis exerts anti-diabetic activity through the action on -cells of pancreas

809,810 Biomaterials and tissue engineering The process of liver repair and regeneration relies on the ECM and the extracellular niche, which support cellmatrix and cellcell interactions

Studies show it can protect nerve tissue from damage and support recovery after nerve injuries

Lactate modulates cellular metabolism through histone lactylation-mediated gene expression in non-small cell lung cancer