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Among the studies that do analyze doseresponse relationships, there is large variation in the units and dose categories used in reporting their findings (for example, the use of pack-years or cigarettes per day) 24,25 , which complicates the comparability and consolidation of evidence

FDA will provide additional details on this issue as they become available. The increased age restriction for tobacco purchases is one of several provisions outside of the spending measures themselves attached to the broader $1.4 trillion spending agreement

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On December 16, 1873, and 15 days ahead of schedule, the "last spike" ceremony was held in Tacoma

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