Optimization of PEGylation, stealth coatings, and TME-responsive release mechanisms is essential to strike a balance between efficacy and biocompatibility [134]
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Anionic (AL) and cationic (CL) hydrogenated lecithin-based liposomes were obtained as GHK-Cu skin delivery systems using the thin-film hydration method combined with freeze-thaw cycles and the extrusion process