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The superimposition of these two effects enhances the anti-apoptotic effect and reduces the dosage requirement of a single component, providing a potential solution for adjuvant therapy to cisplatin chemotherapy, reducing side effects and improving the quality of life of patients (Primadewi et al., 2023)

Pharmacy references commonly describe about 1 mL once or twice weekly, given subcutaneously or intramuscularly

Local ice application typically lasts 15-20 minutes per session, limited to prevent tissue damage from prolonged cold exposure

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10.1007/s10803-014-2205-8 101 McCafferyP.DeutschC