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doi: 10.1056/NEJM200006153422407 8 PrietoD

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Takigawa N

Similarly, in lung fibrosis, inhibition of the Nrf2 pathway is closely associated with elevated levels of oxidative stress in fibrotic tissues, which in turn triggers the abnormal deposition of fibrous components such as collagen, leading to a post-ferroptotic state in lung tissue cells [8, 9]