TRAP-1 supports tumor growth by promoting glycolysis, inhibiting succinate dehydrogenase, and activating cytochrome-c oxidase, 234,235,236 although reduced TRAP-1 expression at later stages has been linked to enhanced motility and invasion, suggesting context-dependent roles
We confirmed that the C-terminus region of SdeA is necessary to its Golgi localization by expressing the N-terminal-truncated SdeA 909-C in cells (Fig
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