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These targeted signaling molecules are either part of a signaling cascade, or transcription factor, or an enzyme that further generates signaling mediators (e -TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner

Fetal inflammation increases ROS production in the mitochondria, which can potentially lead to neuroinflammation, neuronal development dysfunction, and ASD [83,84]

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Vitamin C further contributes to antioxidant recycling and supports normal immune function, while Selenium plays an important role in supporting antioxidant enzyme activity