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Potential Benefits & Side Effects Observations from preclinical and early research literature

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Levring et al., 2015)

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 30% by weight of the viscosity modulating agent(s)

Proven Benefits of DSIP include: Deep Sleep Induction: DSIP targets the brain to increase delta-wave activity, which corresponds to the deepest, most restorative stage of sleep, aiding physical and cognitive recovery

(2021) have developed a validated questionnaire for subjective PEM assessment (Jason et al., 2021) which has been translated into multiple languages