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Learned helplessness Behavioural pattern that occurs when animals are repeatedly exposed to aversive stimuli that cannot be controlled or from which the animal cannot escape

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AARS1 binds directly to lactate, catalyzes the adenosine triphosphate (ATP)-dependent synthesis of lactate-AMP and mediates widespread lysine lactylation, including that of p53

It may be related to decreased collagen turnover and reduced production of the precursor proteins from which GHK is naturally released