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Keywords: Uric acid, Neurodegenerative diseases, Ageing, Oxidative stress, Reactive oxygen species Introduction The umbrella term neurodegenerative disease refers to the gradual pathological decline of neurons in particular neural circuit, commonly involving conditions such as Alzheimers disease (AD), Parkinsons disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS) [1]

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