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BMAL1 stabilizers (e.g., circadian-synchronized Fer-1 analogs) and SOCS1 demethylating agents are in preclinical testing to reverse death resistance

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10.1016/j.bbadis.2015.12.016 220 NewmanA

A mouse metabolises on a faster clock than a human, and a controlled diet in a cage is not a free-living human diet so even the week-numbers above should be read as the shape of a gradual response, not a promise that a human would see anything on the same calendar