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Results of individual studies differed, and the differences may have been related to the dose and duration of grape seed extract supplementation and characteristics of the study participants

Additionally, proteins such as acetyl CoA carboxylase (ACC), acyl-CoA synthetase long-chain family member 4 (ACSL4), lysophosphatidylcholine acyltransferase 3 (LPCAT3), and lipoxygenases (LOX) influence PUFA metabolism and oxidation, while glutathione peroxidase 4 (GPX4) fulfills a crucial role in the antioxidant system by directly converting lipid hydroperoxides to lipid alcohols [16, 17]

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Nature and science of sleep