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The primary objective is to determine safety through adverse event (AE) monitoring, vitals, and laboratory assessments

305 At the therapeutic level, therapeutic vaccines targeting Arg 1 have been shown to activate antitumor immunity in a variety of syngeneic mouse tumor models such as lung cancer, melanoma, and colon cancer, and the combination of Arg 1 vaccine with anti-PD-1 antibody can increase T cell infiltration, inhibit myeloid cell function, and increase the ratio of tumor-infiltrating M1/M2 macrophages

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It is wise to monitor how the body feels after any treatment and follow any guidelines provided by the clinical staff, such as staying hydrated or avoiding strenuous exercise immediately after the injection