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Unfortunately, studies on this topic have mainly focused on normalising serum B12 concentrations with oral supplementation and should be interpreted with caution since the specific goal of treatment in symptomatic B12 deficiency is alleviating symptoms, and NOT to normalize B12 concentrations in the blood

Hydroxocobalamin and adenosylcobalamin also exist but see less use in standard wellness care settings

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Additionally it was noted that in the rats treated with AOD9604, there were increased rates of lipolytic activity, as well as no negative effect on insulin sensitivity which has been seen in animals treated with human growth hormone ( A similar study conducted by Heffernan et