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The method for synthesizing Cagrilintide as claimed in claim 1 or 4, wherein the cleavage reagent is TFA EDT TIS H 2 The volume ratio of O is 87.5:5:2.5: 5

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Imai and colleagues aim to clarify the critical inter-tissue communications among the hypothalamus, skeletal muscle, and adipose tissue in governing mammalian aging and lifespan