The primary outcomeweight losswas negative: the AOD-9604 treatment groups demonstrated no statistically significant reduction in body weight compared to placebo
Histological analysis of adipose tissue from 5-Amino-1MQ-treated animals reveals increased presence of multilocular brown-like adipocytes, increased mitochondrial density, elevated expression of UCP1 and other thermogenic markers, and reduced adipocyte size
Even though it is a great procedure for anybody with stubborn fat in certain body parts like the abdomen, love handles, or arms, it is not the right procedure for everybody
This doesnt mean it isnt safe or effective - this simply means there havent been studies (or the roughly $3 million in fees) submitted to the FDA for their review
PT-141 is supplied strictly for laboratory research use 1,2,4
Cognitive function, assessed by the MMSE and clock test, and mood, measured by the GDS-15, were evaluated at baseline and study end