ghk-cu tolerance desensitization loss of effectiveness antibody formation long-term use Biological efficacy after ionic-liquid loading. (a) Cellular Frontiers ghk-cu tolerance desensitization loss of

[DOI] [PMC free article] [PubMed] [Google Scholar] 544

(June 1998)

S., Stensballe, A., Jensen, O

Side effects from B12 supplementation are uncommon but may include: Mild gastrointestinal symptoms such as nausea or diarrhoea, typically with very high oral doses Headache or dizziness in some individuals Skin reactions (rash, itching) at injection sites when using intramuscular preparations Rare but serious allergic reactions, including anaphylaxis with injectable forms Hypokalaemia (low potassium) may occur during rapid correction of severe megaloblastic anaemia If you experience symptoms of a severe allergic reaction (difficulty breathing, severe rash, swelling of face or throat) after taking B12, seek immediate medical attention

Fourth, well-designed human trials in a specific, measurable indication (rather than broad anti-aging framing) would be needed before any efficacy claim could be made

HYGIENE A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g