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Nucleic Acids Res 41 , 85378545, (2013)

TGR is a 130 kDa obligate homodimer as the functional stereochemistry of the FAD redox site in each subunit is generated by protein dimerization

We demonstrated that GSB-106 acted as a partial TrkB receptor agonist and transactivation mechanisms also could contribute to pro-survival properties of the compound

When Copper Becomes Relevant Copper toxicity from therapeutic peptides is essentially unreported at standard doses

These mechanisms collectively improve drug bioavailability and cytotoxicity in tumor cells

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