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Although scientists know that NASH is associated with elevated blood levels of an amino acid called homocysteine, they didn't know what role, if any, it plays in the development of the disorder

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49% of subjects were serological negative at baseline

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In rodent and primate metabolic models, amylin analogue administration has been shown to attenuate glucagon-driven hepatic glucose output and reduce postprandial glycemic excursions, independently of insulin secretion (Verchere et al., Proceedings of the National Academy of Sciences, 1996