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The absence of serious adverse events in short-term trials does not establish long-term safety, particularly given the compound's prolonged use in underground communities

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The FDA explains that compounded drugs are not FDA-approved , meaning the agency does not verify their safety, effectiveness, or quality before marketing (see Compounding and the FDA: Questions and Answers )

The dose ranges studied spanned from 0.25 mg to 54 mg, allowing for assessment of dose-response relationships in adverse effect profiles

This has enabled deeper investigation into molecular mechanisms and biochemical regulatory processes