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First, we compared the whole metabolome in our four study groups

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Mukherjee SB, Aravinda S, Gopalakrishnan B et al (1999) Secretion of glutathione S-transferase isoforms in the seminiferous tubular fluid, tissue distribution and sex steroid binding by rat GSTM1

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NGS, Next-generation sequencing

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current knowledge, future clinical and translational research questions

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Slows early signs of ageing

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Most importantly, the results of our study show that chronic fatigue, depression and anxiety symptoms in Long COVID are all manifestations of the same core, which is strongly associated with OSTOX/ANTIOX and inflammatory signs There is now evidence that major depression, GAD and chronic fatigue syndrome are IO&NS-related disorders characterized by increased levels of inflammatory mediators, including CRP, oxidative damage to lipids with increased aldehyde formation, damage to proteins, increased NO production and hypernityrosylation and lowered antioxidant levels including zinc, GSH and Gpx and TAC [28, 31, 81, 112]

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