Deep hydration without heaviness
Avoid Triggers The first step is to avoid anything that worsens melasma, such as: Excess sun exposure Hormonal medications (like contraceptive pills) Skincare products with harsh chemicals Topical Medications and Creams Your dermatologist may prescribe creams containing: Cysteamine Methimazole Azelaic acid Hydroquinone Tretinoin Other active ingredients known to lighten dark patches include: Arbutin Glutathione Licorice extract Mequinol Vitamin C Professional Treatments For deeper or resistant pigmentation, dermatologists may recommend: Chemical peels exfoliate and resurface uneven tone Laser therapy selectively targets dark pigment Microneedling stimulates skin renewal and product absorption Platelet-rich plasma (PRP) promotes healing and reduces pigmentation Key Takeaways There are different types of hyperpigmentation, and melasma is one of them

Mesotherapy Mechanism: Multiple intradermal microinjections of vitamins, minerals, peptides, and HA via standard hypodermic needles or a mesotherapy gun
Additionally, a randomized, double-blind, placebo-controlled trial in 162 elderly people (70 years) with mild vitamin B 12 deficiency found that vitamin B 12 supplementation for 24 weeks, alone or in combination with folic acid, did not improve memory performance (117)
Adding peptides to conventional treatment foundations Layering benefits: Start with proven conventional treatments (pressure-lowering drops, AREDS2, glucose control)
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