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Doses are usually smaller than IV infusions, given more frequently

Since vitamin B12 supports red blood cell production (via ODS), it is conceivable that when a vitamin B12 deficiency is treated with high dosage supplementation, the result may be the overproduction of red blood cells

The absence of standardized human dosing makes the threshold for digestive side effects in humans undetermined

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Testing should also consider possible iron deficiency anaemia, macrocytosis, and take into account people on a vegan diet and individuals with a gastrointestinal disorder associated with a vitamin B12 deficiency (see Table 2)[17]