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African trypanosomiasis with special reference to Egyptian Trypanosoma evansi : is it a neglected zoonosis

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As crucial regulators of local immune responses and tissue repair, macrophages in diabetic wounds show dysregulated switching from M1 to M2, resulting in a poor regenerative environment, exacerbated tissue damage, and delayed wound healing 63

T cells in suicidal depressive individuals exhibit predominantly Th1 characteristics, whereas T cells in nonsuicidal depressed patients display Th2 characteristics [109]

Possible heterogeneity may also mean that one single biological measure may not be feasible as a marker for ME/CFS