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[100] Cannabis smoking was common in the Middle East before the arrival of tobacco, and was early on a common social activity that centered around the type of water pipe called a hookah

DGLAP2 belongs to a gene family that encodes proteins that are involved in the molecular organization of synapses and in neuronal cell signaling and has been associated with progressive epilepsy with intellectual disabilities along with other CNS disorders such as ASD and schizophrenia [5456]

Despite a popular notion, Weed or Marijuana is not a gateway drug and must be considered as a potent substance

PMID 38730332

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The Long Term: Weeks 2-4 The first week produces the majority of withdrawal symptoms